WHO-AIIMS seroprevalence survey outcome ‘positive’; larger nationwide sample size needed for comprehensive results: Guleria | India News – Times of India

New Delhi: AIIMS Delhi Director Dr Randeep Guleria on Friday said that the results of a joint study by the World Health Organization (WHO) and AIIMS, which found that covid-19 seroprevalence was in the under-18 age group and per3.5 per cent in the under-18 age group, were “positive”. “.
However, he noted the need for a larger nationwide sample size for broader results. “The results of the survey are positive. It is highly reassuring that if it happens here, it will happen in other parts of the country as well,” Dr Guleria told ANI.
The study noted that there was no statistically significant difference in prevalence between adults and children. Talking about this, Dr. Gularia said, “This study also showed sero surveillance in children who did not know they had.
Infected. Under the age of 18, it was found that more than 50 percent of children and in some areas, more than 80% of children in urban and rural areas, had antibodies, meaning they were already infected and had developed antibodies. ”
Commenting on the results of the survey, which surveyed .32.3 per cent overall, more than half of the rural population, showed evidence of past infections, AIMS Delhi director said that based on this data, a large number of children are less likely to be infected with Kovid-19.
“These issues indicate two things – firstly, a large number of children in our country get mild infections and recover, and secondly, significant children in our country have already got an infection. Therefore, they are less likely to be re-infected. Children are less likely to get a serious infection or a large number of children. ”
However, Dr. Guleria said, “If you want to be more realistic, your antibodies should be neutral. See” “There are other protections for protection that we do not measure anti. Some people have cell-mediated immunity. ”
“Once someone is infected with covidosis, the antibodies begin to decrease within the next four to six months, but the person’s cell-mediated immunity will continue for months and years.”
Speaking further, the head of AIIMS Delhi added, “One’s bone marrow will also have memory cells, it will remember the signature of the virus through these memory cells. So whenever there is any exposure to the virus, the memory cells stimulate the body and the bone marrow and other cells kill the virus.” Starts producing neutral antibodies in bulk.
The stork-covi-2 sero-positivity rate is higher in children than in the adult population. Thus, it is unlikely that any future third wave by the Covid-1 var var variant will inadvertently affect children two years of age or older.
“When a large number of samples are being collected and a large number of people are being monitored under sero surveillance, you will see the common surrogate marker and the antibody will see it,” Dr Guleria said.
Surrogate markers are defined as biomarkers that are able to predict clinical outcomes.
“This study was done recently and thus more recent data is available because it also includes part of the second wave and tried to look at both children and adults,” Dr. Guleria said.
However, he said, “Out of 10,000, only 4,509 analyzes require a larger sample size and the country needs to be represented for its comprehensive results. This survey looks at a few specific areas. The ICMR is already monitoring a series. Survey in the country. ”
The sero survey among children was conducted in the urban rehabilitation colonies of Delhi, Delhi Palli (villages of Faridabad district under Delhi-NCR), Bhubaneswar Grameen, Gorakhpur Palli and Agartala villages.
The data collection period was between March 15, 2021 to June 10, 2021, and total serum antibodies against the SARS-Cavi-2 virus were qualitatively assessed using a standard ELISA kit.

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