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Vaccines are working against infection, severe disease of Covid-19, reveals study | India News – Times of India


NEW DELHI: Christian Medical College, Vellore, a 2,600-bed tertiary care hospital in India with 10,600 staff, has vaccinated 84.8 per cent of the staff, most of whom have got Kovidshield and the rest in India. Covaxin has been obtained by the biotech, a latest research conducted on healthcare workers has revealed.
“A 2,600-bed tertiary care hospital with 10,600 staff at Christian Medical College, Vellore, India, 8,991 employees (84.8 percent) were vaccinated between January 21 and April 30. The majority (93.4%) received the Covishield, Oxford-AstraZeneca vaccine Manufactured by Serum Institute of India, and the remainder, Covaxin, a killed virus vaccine, manufactured by Bharat Biotech, India,” said the study, “by CMC Vellore” for vaccines against infection and acute illness of COVID-19. working against”.
Dr. Joy J. Maimon, Professor in the Department of Transfusion Medicine, CMC Vellore is the corresponding author of the preprint study.
“We report incidences of symptomatic COVID-19 infection among HCWs between February 21 and May 19. Among 1,350 employees who tested positive on RT-PCR, the average (interquartile range) age was 33 years (27–41) The female:male ratio was 3 : 2. The median time to development of infection from the first dose was 77 (62–89) days and coincided with the second peak in India during April and May 2021,” the study said. is.
Professor Dr Gagandeep Kang, CMC Vellore tweeted, “Vaccines are working! Good against infection (in healthcare = high transmission), great against critical illness. Here is the first data from healthcare workers of Medical College, Vellore, Which is being led by Joy Mamon. .
This research has been retrospectively reviewed and found that 33 health care workers (HCWs) developed infections within two weeks of the second dose of the vaccine. In fully vaccinated HCWs (n=7080), 679 (9.6 percent) developed infection at 47 days (34–58) after the second dose.
But the risk of infection in fully vaccinated HCWs was lower than in those who were not vaccinated. The study said, “The risk of infection among fully vaccinated HCWs was significantly lower than among non-vaccinated HCWs (relative risk (RR) 0.35, 95 percent confidence interval (CI) 0.32–0.39). ”
HCWs who were fully vaccinated required fewer hospitalizations, oxygen therapy, and even ICU admission.
Similarly, vaccination with two doses reduced hospitalization (RR 0.23; 95 percent CI 0.16–0.32), need for oxygen therapy (RR 0.08; 95 percent CI 0.03–0.26) and ICU admission (RR 0.06; 95 percent CI). 0.01) -0.27). The protective effect of vaccination for prevention of infection, hospitalization, oxygen requirement and ICU admission was 65 percent, 77 percent, 92 percent and 94 percent, respectively.”
“The only staff member to have died since the start of the epidemic had multiple co-morbidities and had not received the vaccine. Subgroup analysis on the efficacy of the two vaccines was not possible because of the few HCWs receiving covaccine. Some HCWs (17 percent) ) ) could not take the second dose despite the availability of vaccine initially due to lack of vaccine and later due to change in guidelines on the interval between doses.
There are many other studies conducted by other countries that prove that vaccination is protective.
A study of 23,324 HCWs in the UK reported a vaccine coverage of 89 per cent. During the two-month follow-up, 80 participants (3.8 percent) were vaccinated and 977 (38 percent) unvaccinated had symptomatic and asymptomatic infections.
In a Jerusalem study, 366 (6.9 percent) of 5,297 vaccinated HCWs and 213 of 754 non-vaccinated individuals had infection within two months. A third study from California (n=28,184) showed that only 37 HCWs who had received two doses of the vaccine tested positive.
It said, “Our study confirms these studies suggest that vaccination is protective, although we did not look at the forms responsible for the large-scale second wave. Beyond the immediate, public health impacts include cost-effective protection from infection, disease severity, an intervention to reduce and effectively break the chain of transmission. Even as many states chose to restrict movement to reduce the strain on the health care system, we feel that the offensive And future waves may best be prevented or at least minimized through widespread vaccination.”


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